Resveratrol inhibits IL-33–mediated mast cell activation by targeting the MK2/3–PI3K/Akt axis

Interleukin-33 (IL-33)/ST2–mediated mast cell activation plays important roles in the pathophysiology of allergic diseases. Hence, pharmacologically targeting the IL-33/ST2 pathway in mast cells could help to treat such diseases. We found that resveratrol inhibits IL-33/ST2–mediated mast cell activa...

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Detalles Bibliográficos
Autores principales: Nakajima, Shotaro, Ishimaru, Kayoko, Kobayashi, Anna, Yu, Guannan, Nakamura, Yuki, Oh-oka, Kyoko, Suzuki-Inoue, Katsue, Kono, Koji, Nakao, Atsuhito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895112/
https://www.ncbi.nlm.nih.gov/pubmed/31804564
http://dx.doi.org/10.1038/s41598-019-54878-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895112/
https://www.ncbi.nlm.nih.gov/pubmed/31804564
http://dx.doi.org/10.1038/s41598-019-54878-5

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