Withdrawal from escalated cocaine self-administration impairs reversal learning by disrupting the effects of negative feedback on reward exploitation: a behavioral and computational analysis

Addiction is regarded as a disorder of inflexible choice with behavior dominated by immediate positive rewards over longer-term negative outcomes. However, the psychological mechanisms underlying the effects of self-administered drugs on behavioral flexibility are not well understood. To investigate...

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Detalles Bibliográficos
Autores principales: Zhukovsky, Peter, Puaud, Mickael, Jupp, Bianca, Sala-Bayo, Júlia, Alsiö, Johan, Xia, Jing, Searle, Lydia, Morris, Zoe, Sabir, Aryan, Giuliano, Chiara, Everitt, Barry J., Belin, David, Robbins, Trevor W., Dalley, Jeffrey W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895115/
https://www.ncbi.nlm.nih.gov/pubmed/30952156
http://dx.doi.org/10.1038/s41386-019-0381-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895115/
https://www.ncbi.nlm.nih.gov/pubmed/30952156
http://dx.doi.org/10.1038/s41386-019-0381-0

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