Japanese encephalitis vaccine-specific envelope protein E138K mutation does not attenuate virulence of West Nile virus

West Nile (WNV) and Japanese encephalitis viruses (JEV) are closely related, mosquito-borne neurotropic flaviviruses. Although there are no licensed human vaccines for WNV, JEV has multiple human vaccines, including the live, attenuated vaccine SA14-14-2. Investigations into determinants of attenuat...

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Detalles Bibliográficos
Autores principales: Kaiser, Jaclyn A., Luo, Huanle, Widen, Steven G., Wood, Thomas G., Huang, Claire Y-H., Wang, Tian, Barrett, Alan D. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895119/
https://www.ncbi.nlm.nih.gov/pubmed/31839996
http://dx.doi.org/10.1038/s41541-019-0146-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895119/
https://www.ncbi.nlm.nih.gov/pubmed/31839996
http://dx.doi.org/10.1038/s41541-019-0146-0

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