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Heterogeneity and dynamics of active Kras-induced dysplastic lineages from mouse corpus stomach
Dysplasia is considered a key transition state between pre-cancer and cancer in gastric carcinogenesis. However, the cellular or phenotypic heterogeneity and mechanisms of dysplasia progression have not been elucidated. We have established metaplastic and dysplastic organoid lines, derived from Mist...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895174/ https://www.ncbi.nlm.nih.gov/pubmed/31804471 http://dx.doi.org/10.1038/s41467-019-13479-6 |