Heterogeneity and dynamics of active Kras-induced dysplastic lineages from mouse corpus stomach

Dysplasia is considered a key transition state between pre-cancer and cancer in gastric carcinogenesis. However, the cellular or phenotypic heterogeneity and mechanisms of dysplasia progression have not been elucidated. We have established metaplastic and dysplastic organoid lines, derived from Mist...

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Detalles Bibliográficos
Autores principales: Min, Jimin, Vega, Paige N., Engevik, Amy C., Williams, Janice A., Yang, Qing, Patterson, Loraine M., Simmons, Alan J., Bliton, R. Jarrett, Betts, Joshua W., Lau, Ken S., Magness, Scott T., Goldenring, James R., Choi, Eunyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895174/
https://www.ncbi.nlm.nih.gov/pubmed/31804471
http://dx.doi.org/10.1038/s41467-019-13479-6

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