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Pyroptosis is a critical inflammatory pathway in the placenta from early onset preeclampsia and in human trophoblasts exposed to hypoxia and endoplasmic reticulum stressors

Systemic manifestation of preeclampsia (PE) is associated with circulating factors, including inflammatory cytokines and damage-associated molecular patterns (DAMPs), or alarmins. However, it is unclear whether the placenta directly contributes to the increased levels of these inflammatory triggers....

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Detalles Bibliográficos
Autores principales: Cheng, Shi-Bin, Nakashima, Akitoshi, Huber, Warren J., Davis, Sarah, Banerjee, Sayani, Huang, Zheping, Saito, Shigeru, Sadovsky, Yoel, Sharma, Surendra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895177/
https://www.ncbi.nlm.nih.gov/pubmed/31804457
http://dx.doi.org/10.1038/s41419-019-2162-4