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LRRC8/VRAC channels exhibit a noncanonical permeability to glutathione, which modulates epithelial-to-mesenchymal transition (EMT)

Volume-regulated anion channels (VRAC) are chloride channels activated in response to osmotic stress to regulate cellular volume and also participate in other cellular processes, including cell division and cell death. Recently, members of the LRRC8 family have been identified as the main contributo...

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Detalles Bibliográficos
Autores principales: Friard, Jonas, Corinus, Alain, Cougnon, Marc, Tauc, Michel, Pisani, Didier F., Duranton, Christophe, Rubera, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895240/
https://www.ncbi.nlm.nih.gov/pubmed/31804464
http://dx.doi.org/10.1038/s41419-019-2167-z