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Zika virus NS3 is a canonical RNA helicase stimulated by NS5 RNA polymerase

Zika virus is a positive single-strand RNA virus whose replication involved RNA unwinding and synthesis. ZIKV NS3 contains a helicase domain, but its enzymatic activity is not fully characterized. Here, we established a dsRNA unwinding assay based on the FRET effect to study the helicase activity of...

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Detalles Bibliográficos
Autores principales: Xu, Shan, Ci, Yali, Wang, Leijie, Yang, Yang, Zhang, Leiliang, Xu, Caimin, Qin, Chengfeng, Shi, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895266/
https://www.ncbi.nlm.nih.gov/pubmed/31361901
http://dx.doi.org/10.1093/nar/gkz650