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Zika virus NS3 is a canonical RNA helicase stimulated by NS5 RNA polymerase
Zika virus is a positive single-strand RNA virus whose replication involved RNA unwinding and synthesis. ZIKV NS3 contains a helicase domain, but its enzymatic activity is not fully characterized. Here, we established a dsRNA unwinding assay based on the FRET effect to study the helicase activity of...
Autores principales: | Xu, Shan, Ci, Yali, Wang, Leijie, Yang, Yang, Zhang, Leiliang, Xu, Caimin, Qin, Chengfeng, Shi, Lei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895266/ https://www.ncbi.nlm.nih.gov/pubmed/31361901 http://dx.doi.org/10.1093/nar/gkz650 |
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