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Inositol pyrophosphates impact phosphate homeostasis via modulation of RNA 3′ processing and transcription termination

Fission yeast phosphate acquisition genes pho1, pho84, and tgp1 are repressed in phosphate-rich medium by transcription of upstream lncRNAs. Here, we show that phosphate homeostasis is subject to metabolite control by inositol pyrophosphates (IPPs), exerted through the 3′-processing/termination mach...

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Detalles Bibliográficos
Autores principales: Sanchez, Ana M, Garg, Angad, Shuman, Stewart, Schwer, Beate
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895273/
https://www.ncbi.nlm.nih.gov/pubmed/31276588
http://dx.doi.org/10.1093/nar/gkz567