Evolutionary coupling analysis identifies the impact of disease-associated variants at less-conserved sites

Genome-wide association studies have discovered a large number of genetic variants in human patients with the disease. Thus, predicting the impact of these variants is important for sorting disease-associated variants (DVs) from neutral variants. Current methods to predict the mutational impacts dep...

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Detalles Bibliográficos
Autores principales: Kim, Donghyo, Han, Seong Kyu, Lee, Kwanghwan, Kim, Inhae, Kong, JungHo, Kim, Sanguk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895274/
https://www.ncbi.nlm.nih.gov/pubmed/31199866
http://dx.doi.org/10.1093/nar/gkz536

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895274/
https://www.ncbi.nlm.nih.gov/pubmed/31199866
http://dx.doi.org/10.1093/nar/gkz536

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