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Completion of LINE integration involves an open ‘4-way’ branched DNA intermediate

Long Interspersed Elements (LINEs), also known as non-LTR retrotransposons, encode a multifunctional protein that reverse transcribes its mRNA into DNA at the site of insertion by target primed reverse transcription. The second half of the integration reaction remains very poorly understood. Second-...

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Detalles Bibliográficos
Autores principales: Khadgi, Brijesh B, Govindaraju, Aruna, Christensen, Shawn M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895275/
https://www.ncbi.nlm.nih.gov/pubmed/31392993
http://dx.doi.org/10.1093/nar/gkz673