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Molecular affinity rulers: systematic evaluation of DNA aptamers for their applicabilities in ELISA

Many nucleic acid aptamers that bind to target molecules have been reported as antibody alternatives. However, while the affinities of aptamers vary widely, little is known about the relationship between the affinities and their applicabilities for practical use. Here, we developed molecular affinit...

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Detalles Bibliográficos
Autores principales: Kimoto, Michiko, Shermane Lim, Yun Wei, Hirao, Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895277/
https://www.ncbi.nlm.nih.gov/pubmed/31392985
http://dx.doi.org/10.1093/nar/gkz688