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Engineering DNA recognition and allosteric response properties of TetR family proteins by using a module-swapping strategy
The development of synthetic biological systems requires modular biomolecular components to flexibly alter response pathways. In previous studies, we have established a module-swapping design principle to engineer allosteric response and DNA recognition properties among regulators in the LacI family...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895282/ https://www.ncbi.nlm.nih.gov/pubmed/31392336 http://dx.doi.org/10.1093/nar/gkz666 |