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Mammalian NSUN2 introduces 5-methylcytidines into mitochondrial tRNAs
Post-transcriptional modifications in mitochondrial tRNAs (mt-tRNAs) play critical roles in mitochondrial protein synthesis, which produces respiratory chain complexes. In this study, we took advantage of mass spectrometric analysis to map 5-methylcytidine (m(5)C) at positions 48–50 in eight mouse a...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895283/ https://www.ncbi.nlm.nih.gov/pubmed/31287866 http://dx.doi.org/10.1093/nar/gkz575 |