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Mammalian NSUN2 introduces 5-methylcytidines into mitochondrial tRNAs

Post-transcriptional modifications in mitochondrial tRNAs (mt-tRNAs) play critical roles in mitochondrial protein synthesis, which produces respiratory chain complexes. In this study, we took advantage of mass spectrometric analysis to map 5-methylcytidine (m(5)C) at positions 48–50 in eight mouse a...

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Detalles Bibliográficos
Autores principales:	Shinoda, Saori, Kitagawa, Sho, Nakagawa, Shinichi, Wei, Fan-Yan, Tomizawa, Kazuhito, Araki, Kimi, Araki, Masatake, Suzuki, Takeo, Suzuki, Tsutomu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	RNA and RNA-protein complexes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895283/ https://www.ncbi.nlm.nih.gov/pubmed/31287866 http://dx.doi.org/10.1093/nar/gkz575

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