Induction of NKG2D ligand expression on tumor cells by CD8(+) T cell engagement-mediated activation of nuclear factor-kappa B and p300/CBP-associated factor

The ligands for the natural killer group 2 (NKG2D) protein render tumor cells susceptible to NKG2D-dependent immune cell attack. However, cancer cells escape from immune surveillance by downregulating NKG2D ligands. We previously discovered that engagement of activated CD8(+) T cells and tumor cells...

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Detalles Bibliográficos
Autores principales: Hu, Jiemiao, Xia, Xueqing, Gorlick, Richard, Li, Shulin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895417/
https://www.ncbi.nlm.nih.gov/pubmed/31427736
http://dx.doi.org/10.1038/s41388-019-0960-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895417/
https://www.ncbi.nlm.nih.gov/pubmed/31427736
http://dx.doi.org/10.1038/s41388-019-0960-x

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