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Induction of NKG2D ligand expression on tumor cells by CD8(+) T cell engagement-mediated activation of nuclear factor-kappa B and p300/CBP-associated factor
The ligands for the natural killer group 2 (NKG2D) protein render tumor cells susceptible to NKG2D-dependent immune cell attack. However, cancer cells escape from immune surveillance by downregulating NKG2D ligands. We previously discovered that engagement of activated CD8(+) T cells and tumor cells...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895417/ https://www.ncbi.nlm.nih.gov/pubmed/31427736 http://dx.doi.org/10.1038/s41388-019-0960-x |