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A Tppp3(+)Pdgfra(+) tendon stem cell population contributes to regeneration and reveals a shared role for PDGF signalling in regeneration and fibrosis

Tendon injuries cause prolonged disability and never recover completely. Current mechanistic understanding of tendon regeneration is limited. Here we use single cell transcriptomics to identify a tubulin polymerization-promoting protein family member 3-expressing (Tppp3(+)) cell population as potent...

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Detalles Bibliográficos
Autores principales: Harvey, Tyler, Flamenco, Sara, Fan, Chen-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895435/
https://www.ncbi.nlm.nih.gov/pubmed/31768046
http://dx.doi.org/10.1038/s41556-019-0417-z