Vitamin K3 derivative induces apoptotic cell death in neuroblastoma via downregulation of MYCN expression

Neuroblastoma is a pediatric malignant tumor arising from the sympathetic nervous system. The patients with high-risk neuroblastomas frequently exhibit amplification and high expression of the MYCN gene, resulting in worse clinical outcomes. Vitamin K3 (VK3) is a synthetic VK-like compound that has...

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Detalles Bibliográficos
Autores principales: Yoda, Hiroyuki, Nakayama, Toshimitsu, Miura, Motofumi, Toriyama, Masaharu, Motohashi, Shigeyasu, Suzuki, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895568/
https://www.ncbi.nlm.nih.gov/pubmed/31844686
http://dx.doi.org/10.1016/j.bbrep.2019.100701

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895568/
https://www.ncbi.nlm.nih.gov/pubmed/31844686
http://dx.doi.org/10.1016/j.bbrep.2019.100701

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