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Vitamin K3 derivative induces apoptotic cell death in neuroblastoma via downregulation of MYCN expression
Neuroblastoma is a pediatric malignant tumor arising from the sympathetic nervous system. The patients with high-risk neuroblastomas frequently exhibit amplification and high expression of the MYCN gene, resulting in worse clinical outcomes. Vitamin K3 (VK3) is a synthetic VK-like compound that has...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895568/ https://www.ncbi.nlm.nih.gov/pubmed/31844686 http://dx.doi.org/10.1016/j.bbrep.2019.100701 |