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Therapeutic targeting of circ‐CUX1/EWSR1/MAZ axis inhibits glycolysis and neuroblastoma progression

Aerobic glycolysis is a hallmark of metabolic reprogramming in tumor progression. However, the mechanisms regulating glycolytic gene expression remain elusive in neuroblastoma (NB), the most common extracranial malignancy in childhood. Herein, we identify that CUT‐like homeobox 1 (CUX1) and CUX1‐gen...

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Detalles Bibliográficos
Autores principales: Li, Huanhuan, Yang, Feng, Hu, Anpei, Wang, Xiaojing, Fang, Erhu, Chen, Yajun, Li, Dan, Song, Huajie, Wang, Jianqun, Guo, Yanhua, Liu, Yang, Li, Hongjun, Huang, Kai, Zheng, Liduan, Tong, Qiangsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895612/
https://www.ncbi.nlm.nih.gov/pubmed/31709724
http://dx.doi.org/10.15252/emmm.201910835