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Cobalt protoporphyrin IX increases endogenous G‐CSF and mobilizes HSC and granulocytes to the blood

Granulocyte colony‐stimulating factor (G‐CSF) is used in clinical practice to mobilize cells from the bone marrow to the blood; however, it is not always effective. We show that cobalt protoporphyrin IX (CoPP) increases plasma concentrations of G‐CSF, IL‐6, and MCP‐1 in mice, triggering the mobiliza...

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Detalles Bibliográficos
Autores principales: Szade, Agata, Szade, Krzysztof, Nowak, Witold N, Bukowska‐Strakova, Karolina, Muchova, Lucie, Gońka, Monika, Żukowska, Monika, Cieśla, Maciej, Kachamakova‐Trojanowska, Neli, Rams‐Baron, Marzena, Ratuszna, Alicja, Dulak, Józef, Józkowicz, Alicja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895613/
https://www.ncbi.nlm.nih.gov/pubmed/31709729
http://dx.doi.org/10.15252/emmm.201809571