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Interaction of cyclosporine with phenobarbital in cats: a preliminary study

Phenobarbital (PB) decreases the cyclosporine (CsA) blood level in humans. However, the interaction of PB with CsA has not been reported in cats. This study investigated the effects of multiple doses of PB on the pharmacokinetics of CsA in three healthy cats. The treatments included oral CsA 5 mg/kg...

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Detalles Bibliográficos
Autores principales: HOSHINO, Yuki, INDEN, Takanori, OTAKA, Riko, FUKUI, Daisuke, SATOH, Hiroshi, KATAYAMA, Masaaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895620/
https://www.ncbi.nlm.nih.gov/pubmed/31597813
http://dx.doi.org/10.1292/jvms.19-0339