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Autoantibodies Specific for Galactose-Deficient IgA1 in IgA Vasculitis With Nephritis

INTRODUCTION: Patients with IgA nephropathy (IgAN) have elevated serum levels of galactose-deficient IgA1 (Gd-IgA1) that are bound by Gd-IgA1–specific autoantibodies in pathogenic immune complexes. Renal biopsy histopathologic features of IgA vasculitis (IgAV) with nephritis (IgAV-N) are similar to...

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Detalles Bibliográficos
Autores principales: Suzuki, Hitoshi, Moldoveanu, Zina, Julian, Bruce A., Wyatt, Robert J., Novak, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895670/
https://www.ncbi.nlm.nih.gov/pubmed/31844808
http://dx.doi.org/10.1016/j.ekir.2019.08.015