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Closing the Mitochondrial Permeability Transition Pore in hiPSC-Derived Endothelial Cells Induces Glycocalyx Formation and Functional Maturation

Human induced pluripotent stem cells (hiPSCs) are used to study organogenesis and model disease as well as being developed for regenerative medicine. Endothelial cells are among the many cell types differentiated from hiPSCs, but their maturation and stabilization fall short of that in adult endothe...

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Detalles Bibliográficos
Autores principales: Tiemeier, Gesa L., Wang, Gangqi, Dumas, Sébastien J., Sol, Wendy M.P.J., Avramut, M. Cristina, Karakach, Tobias, Orlova, Valeria V., van den Berg, Cathelijne W., Mummery, Christine L., Carmeliet, Peter, van den Berg, Bernard M., Rabelink, Ton J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895683/
https://www.ncbi.nlm.nih.gov/pubmed/31680061
http://dx.doi.org/10.1016/j.stemcr.2019.10.005