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Closing the Mitochondrial Permeability Transition Pore in hiPSC-Derived Endothelial Cells Induces Glycocalyx Formation and Functional Maturation
Human induced pluripotent stem cells (hiPSCs) are used to study organogenesis and model disease as well as being developed for regenerative medicine. Endothelial cells are among the many cell types differentiated from hiPSCs, but their maturation and stabilization fall short of that in adult endothe...
Autores principales: | Tiemeier, Gesa L., Wang, Gangqi, Dumas, Sébastien J., Sol, Wendy M.P.J., Avramut, M. Cristina, Karakach, Tobias, Orlova, Valeria V., van den Berg, Cathelijne W., Mummery, Christine L., Carmeliet, Peter, van den Berg, Bernard M., Rabelink, Ton J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895683/ https://www.ncbi.nlm.nih.gov/pubmed/31680061 http://dx.doi.org/10.1016/j.stemcr.2019.10.005 |
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