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In vivo evidence of cortical amyloid deposition in the adult form of Niemann Pick type C
BACKGROUND: Niemann Pick disease type C (NPC) is a lysosomal lipid storage disorder presenting visceral and neurological impairment with cognitive decline. Neurodegeneration in NPC is associated to deposition of amyloid-β and abnormal tau aggregations likewise Alzheimer disease (AD). Dementia is als...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895717/ https://www.ncbi.nlm.nih.gov/pubmed/31844711 http://dx.doi.org/10.1016/j.heliyon.2019.e02776 |