In vivo evidence of cortical amyloid deposition in the adult form of Niemann Pick type C

BACKGROUND: Niemann Pick disease type C (NPC) is a lysosomal lipid storage disorder presenting visceral and neurological impairment with cognitive decline. Neurodegeneration in NPC is associated to deposition of amyloid-β and abnormal tau aggregations likewise Alzheimer disease (AD). Dementia is als...

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Detalles Bibliográficos
Autores principales: Esposito, Marcello, Dubbioso, Raffaele, Tozza, Stefano, Iodice, Rosa, Aiello, Marco, Nicolai, Emanuele, Cavaliere, Carlo, Salvatore, Marco, Santoro, Lucio, Manganelli, Fiore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895717/
https://www.ncbi.nlm.nih.gov/pubmed/31844711
http://dx.doi.org/10.1016/j.heliyon.2019.e02776

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