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Lipid class composition of membrane and raft fractions from brains of individuals with Alzheimer's disease

Perturbation of the homeostasis of brain membrane lipids has been implicated in the pathomechanism of Alzheimer's disease (AD). The ε4 allele of the apolipoprotein E gene (APOE) confers an increased risk, in a dosage-dependent manner, for brain amyloid-β accumulation and the development of spor...

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Detalles Bibliográficos
Autores principales: Kawatsuki, Akihiro, Morita, Shin-ya, Watanabe, Naoki, Hibino, Emi, Mitsuishi, Yachiyo, Sugi, Takuma, Murayama, Shigeo, Nishimura, Masaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895748/
https://www.ncbi.nlm.nih.gov/pubmed/31867447
http://dx.doi.org/10.1016/j.bbrep.2019.100704