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Lipid class composition of membrane and raft fractions from brains of individuals with Alzheimer's disease
Perturbation of the homeostasis of brain membrane lipids has been implicated in the pathomechanism of Alzheimer's disease (AD). The ε4 allele of the apolipoprotein E gene (APOE) confers an increased risk, in a dosage-dependent manner, for brain amyloid-β accumulation and the development of spor...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895748/ https://www.ncbi.nlm.nih.gov/pubmed/31867447 http://dx.doi.org/10.1016/j.bbrep.2019.100704 |