Complex Formation with Monomeric α-Tubulin and Importin 13 Fosters c-Jun Protein Stability and Is Required for c-Jun’s Nuclear Translocation and Activity

Microtubules are highly dynamic structures, which consist of α- and β-tubulin heterodimers. They are essential for a number of cellular processes, including intracellular trafficking and mitosis. Tubulin-binding chemotherapeutics are used to treat different types of tumors, including malignant melan...

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Detalles Bibliográficos
Autores principales: Kappelmann-Fenzl, Melanie, Kuphal, Silke, Krupar, Rosemarie, Schadendorf, Dirk, Umansky, Viktor, Vardimon, Lily, Hellerbrand, Claus, Bosserhoff, Anja-Katrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895814/
https://www.ncbi.nlm.nih.gov/pubmed/31744174
http://dx.doi.org/10.3390/cancers11111806

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895814/
https://www.ncbi.nlm.nih.gov/pubmed/31744174
http://dx.doi.org/10.3390/cancers11111806

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