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G-Quadruplex Binders Induce Immunogenic Cell Death Markers in Aggressive Breast Cancer Cells

Background: DNA G-quadruplex (G4) structures represent potential anti-cancer targets. In this study, we compared the effect of two G4-targeting compounds, C066-3108 and the gold standard BRACO-19. Methods: In breast and prostate cancer cells, cytotoxicity induced by both molecules was measured by a...

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Detalles Bibliográficos
Autores principales: Di Somma, Sarah, Amato, Jussara, Iaccarino, Nunzia, Pagano, Bruno, Randazzo, Antonio, Portella, Giuseppe, Malfitano, Anna Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895816/
https://www.ncbi.nlm.nih.gov/pubmed/31731707
http://dx.doi.org/10.3390/cancers11111797