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In Vivo Evidence for Voltage-Gated Sodium Channel Expression in Carcinomas and Potentiation of Metastasis

A wide body of evidence suggests that voltage-gated sodium channels (VGSCs) are expressed de novo in several human carcinomas where channel activity promotes a variety of cellular behaviours integral to the metastatic cascade. These include directional motility (including galvanotaxis), pH balance,...

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Detalles Bibliográficos
Autores principales: Djamgoz, Mustafa B. A., Fraser, Scott P., Brackenbury, William J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895836/
https://www.ncbi.nlm.nih.gov/pubmed/31661908
http://dx.doi.org/10.3390/cancers11111675