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Vitamin D Increases CTLA-4 Gene Expression in Patients with Mild to Moderate Ulcerative Colitis

BACKGROUND Ulcerative colitis (UC) is a chronic inflammatory disorder of the large intestine. Cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) is a member of the immunoglobulin superfamily, which binds B7-1 and B7-2 on APCs (antigen-presenting cells), and induces APCs to produce an inhibitory si...

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Detalles Bibliográficos
Autores principales: Sharifi, Amrollah, Vahedi, Homayoon, Honarvar, Mohammad Reza, Alipoor, Behnam, Nikniaz, Zeinab, Rafiei, Hossein, Hosseinzadeh-Attar, Mohammad Javad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iranian Association of Gastroerterology and Hepatology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895856/
https://www.ncbi.nlm.nih.gov/pubmed/31824622
http://dx.doi.org/10.15171/mejdd.2019.149