The RB1 Story: Characterization and Cloning of the First Tumor Suppressor Gene

The RB1 gene is the first described human tumor suppressor gene and plays an integral role in the development of retinoblastoma, a pediatric malignancy of the eye. Since its discovery, the stepwise characterization and cloning of RB1 have laid the foundation for numerous advances in the understandin...

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Detalles Bibliográficos
Autores principales: Berry, Jesse L., Polski, Ashley, Cavenee, Webster K., Dryja, Thaddeus P., Murphree, A. Linn, Gallie, Brenda L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895859/
https://www.ncbi.nlm.nih.gov/pubmed/31683923
http://dx.doi.org/10.3390/genes10110879

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895859/
https://www.ncbi.nlm.nih.gov/pubmed/31683923
http://dx.doi.org/10.3390/genes10110879

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