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Arpp19 Promotes Myc and Cip2a Expression and Associates with Patient Relapse in Acute Myeloid Leukemia

Disease relapse from standard chemotherapy in acute myeloid leukemia (AML) is poorly understood. The importance of protein phosphatase 2A (PP2A) as an AML tumor suppressor is emerging. Therefore, here, we examined the potential role of endogenous PP2A inhibitor proteins as biomarkers predicting AML...

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Detalles Bibliográficos
Autores principales: Mäkelä, Eleonora, Löyttyniemi, Eliisa, Salmenniemi, Urpu, Kauko, Otto, Varila, Taru, Kairisto, Veli, Itälä-Remes, Maija, Westermarck, Jukka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895887/
https://www.ncbi.nlm.nih.gov/pubmed/31717978
http://dx.doi.org/10.3390/cancers11111774