Balancing STAT Activity as a Therapeutic Strategy

Driven by dysregulated IL-6 family member cytokine signaling in the tumor microenvironment (TME), aberrant signal transducer and activator of transcription (STAT3) and (STAT5) activation have been identified as key contributors to tumorigenesis. Following transformation, persistent STAT3 activation...

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Detalles Bibliográficos
Autores principales: Polak, Kelsey L., Chernosky, Noah M., Smigiel, Jacob M., Tamagno, Ilaria, Jackson, Mark W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895889/
https://www.ncbi.nlm.nih.gov/pubmed/31684144
http://dx.doi.org/10.3390/cancers11111716

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895889/
https://www.ncbi.nlm.nih.gov/pubmed/31684144
http://dx.doi.org/10.3390/cancers11111716

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