Targeting Negative and Positive Immune Checkpoints with Monoclonal Antibodies in Therapy of Cancer

The immune checkpoints are regulatory molecules that maintain immune homeostasis in physiological conditions. By sending T cells a series of co-stimulatory or co-inhibitory signals via receptors, immune checkpoints can both protect healthy tissues from adaptive immune response and activate lymphocyt...

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Detalles Bibliográficos
Autores principales: Marhelava, Katsiaryna, Pilch, Zofia, Bajor, Malgorzata, Graczyk-Jarzynka, Agnieszka, Zagozdzon, Radoslaw
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895894/
https://www.ncbi.nlm.nih.gov/pubmed/31717326
http://dx.doi.org/10.3390/cancers11111756

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895894/
https://www.ncbi.nlm.nih.gov/pubmed/31717326
http://dx.doi.org/10.3390/cancers11111756

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