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Targeting Negative and Positive Immune Checkpoints with Monoclonal Antibodies in Therapy of Cancer
The immune checkpoints are regulatory molecules that maintain immune homeostasis in physiological conditions. By sending T cells a series of co-stimulatory or co-inhibitory signals via receptors, immune checkpoints can both protect healthy tissues from adaptive immune response and activate lymphocyt...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895894/ https://www.ncbi.nlm.nih.gov/pubmed/31717326 http://dx.doi.org/10.3390/cancers11111756 |