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Enriching Human Interactome with Functional Mutations to Detect High-Impact Network Modules Underlying Complex Diseases

Rapid progress in high-throughput -omics technologies moves us one step closer to the datacalypse in life sciences. In spite of the already generated volumes of data, our knowledge of the molecular mechanisms underlying complex genetic diseases remains limited. Increasing evidence shows that biologi...

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Detalles Bibliográficos
Autores principales: Cui, Hongzhu, Srinivasan, Suhas, Korkin, Dmitry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895925/
https://www.ncbi.nlm.nih.gov/pubmed/31731769
http://dx.doi.org/10.3390/genes10110933