The Histone Methyltransferase DOT1L Is a Functional Component of Estrogen Receptor Alpha Signaling in Ovarian Cancer Cells

Although a large fraction of high-grade serous epithelial ovarian cancers (OCs) expresses Estrogen Receptor alpha (ERα), anti-estrogen-based therapies are still not widely used against these tumors due to a lack of sufficient evidence. The histone methyltransferase Disruptor of telomeric silencing-1...

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Detalles Bibliográficos
Autores principales: Salvati, Annamaria, Gigantino, Valerio, Nassa, Giovanni, Giurato, Giorgio, Alexandrova, Elena, Rizzo, Francesca, Tarallo, Roberta, Weisz, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895927/
https://www.ncbi.nlm.nih.gov/pubmed/31689915
http://dx.doi.org/10.3390/cancers11111720

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895927/
https://www.ncbi.nlm.nih.gov/pubmed/31689915
http://dx.doi.org/10.3390/cancers11111720

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