Genome-Wide Small RNA Sequencing Identifies MicroRNAs Deregulated in Non-Small Cell Lung Carcinoma Harboring Gain-of-Function Mutant p53

Mutations in the TP53 gene are one of the most frequent events in cancers. Certain missense mutant p53 proteins gain oncogenic functions (gain-of-functions) and drive tumorigenesis. Apart from the coding genes, a few non-coding microRNAs (miRNAs) are implicated in mediating mutant p53-driven cancer...

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Detalles Bibliográficos
Autores principales: Datta, Arindam, Das, Pijush, Dey, Sanjib, Ghuwalewala, Sangeeta, Ghatak, Dishari, Alam, Sk. Kayum, Chatterjee, Raghunath, Roychoudhury, Susanta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895929/
https://www.ncbi.nlm.nih.gov/pubmed/31661871
http://dx.doi.org/10.3390/genes10110852

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895929/
https://www.ncbi.nlm.nih.gov/pubmed/31661871
http://dx.doi.org/10.3390/genes10110852

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