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CNV Detection from Circulating Tumor DNA in Late Stage Non-Small Cell Lung Cancer Patients

While methods for detecting SNVs and indels in circulating tumor DNA (ctDNA) with hybridization capture-based next-generation sequencing (NGS) have been available, copy number variations (CNVs) detection is more challenging. Here, we present a method enabling CNV detection from a 150-gene panel usin...

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Detalles Bibliográficos
Autores principales: Peng, Hao, Lu, Lan, Zhou, Zisong, Liu, Jian, Zhang, Dadong, Nan, Kejun, Zhao, Xiaochen, Li, Fugen, Tian, Lei, Dong, Hua, Yao, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895974/
https://www.ncbi.nlm.nih.gov/pubmed/31739500
http://dx.doi.org/10.3390/genes10110926