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Transient Chemogenetic Inhibition of D1-MSNs in the Dorsal Striatum Enhances Methamphetamine Self-Administration

The dorsal striatum is important for the development of drug addiction; however, the role of dopamine D1 receptor (D1R) expressing medium-sized spiny striatonigral (direct pathway) neurons (D1-MSNs) in regulating excessive methamphetamine intake remains elusive. Here we seek to determine if modulati...

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Detalles Bibliográficos
Autores principales: Oliver, Robert J., Purohit, Dvijen C., Kharidia, Khush M., Mandyam, Chitra D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895983/
https://www.ncbi.nlm.nih.gov/pubmed/31752398
http://dx.doi.org/10.3390/brainsci9110330