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Loss of FBXO9 Enhances Proteasome Activity and Promotes Aggressiveness in Acute Myeloid Leukemia

The hematopoietic system is maintained throughout life by stem cells that are capable of differentiating into all hematopoietic lineages. An intimate balance between self-renewal, differentiation, and quiescence is required to maintain hematopoiesis and disruption of this balance can result in malig...

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Detalles Bibliográficos
Autores principales: Hynes-Smith, R. Willow, Swenson, Samantha A., Vahle, Heather, Wittorf, Karli J., Caplan, Mika, Amador, Catalina, Hyde, R. Katherine, Buckley, Shannon M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895989/
https://www.ncbi.nlm.nih.gov/pubmed/31684170
http://dx.doi.org/10.3390/cancers11111717