Treatment with a Combination of Metformin and 2-Deoxyglucose Upregulates Thrombospondin-1 in Microvascular Endothelial Cells: Implications in Anti-Angiogenic Cancer Therapy

Metformin, the most widely used anti-diabetic drug, also exhibits anti-cancer properties; however, the true potential of metformin as an anticancer drug remains largely unknown. In this study using mouse microvascular endothelial cells (MMECs), we investigated the effects of metformin alone or in co...

Descripción completa

Detalles Bibliográficos
Autores principales: Mathews Samuel, Samson, Satheesh, Noothan Jyothi, Ghosh, Suparna, Büsselberg, Dietrich, Majeed, Yasser, Ding, Hong, Triggle, Chris R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895998/
https://www.ncbi.nlm.nih.gov/pubmed/31698699
http://dx.doi.org/10.3390/cancers11111737

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895998/
https://www.ncbi.nlm.nih.gov/pubmed/31698699
http://dx.doi.org/10.3390/cancers11111737

Ejemplares similares