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DOCK1 Regulates Growth and Motility through the RRP1B-Claudin-1 Pathway in Claudin-Low Breast Cancer Cells

Dedicator of cytokinesis 1 (DOCK1) is a critical regulator of cancer metastasis. Claudins are transmembrane proteins that play a role in epithelial barrier integrity. Due to a loss or low expression of claudins (CLDN), the claudin-low type of triple-negative breast cancer (TNBC) is characterized by...

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Detalles Bibliográficos
Autores principales: Chiang, Shih-Kai, Chang, Wei-Chao, Chen, Shuen-Ei, Chang, Ling-Chu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896004/
https://www.ncbi.nlm.nih.gov/pubmed/31717460
http://dx.doi.org/10.3390/cancers11111762