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Genome Maintenance Proteins Modulate Autoimmunity Mediated Primed Adaptation by the Escherichia coli Type I-E CRISPR-Cas System

Bacteria and archaea use CRISPR-Cas adaptive immunity systems to interfere with viruses, plasmids, and other mobile genetic elements. During the process of adaptation, CRISPR-Cas systems acquire immunity by incorporating short fragments of invaders’ genomes into CRISPR arrays. The acquisition of fra...

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Detalles Bibliográficos
Autores principales: Kurilovich, Elena, Shiriaeva, Anna, Metlitskaya, Anastasia, Morozova, Natalia, Ivancic-Bace, Ivana, Severinov, Konstantin, Savitskaya, Ekaterina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896009/
https://www.ncbi.nlm.nih.gov/pubmed/31683605
http://dx.doi.org/10.3390/genes10110872