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Antitumor Reactive T-Cell Responses Are Enhanced In Vivo by DAMP Prothymosin Alpha and Its C-Terminal Decapeptide

Prothymosin α (proTα) and its C-terminal decapeptide proTα(100–109) were shown to pleiotropically enhance innate and adaptive immune responses. Their activities have been broadly studied in vitro, focusing primarily on the restoration of the deficient immunoreactivity of cancer patients’ leukocytes....

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Detalles Bibliográficos
Autores principales: Birmpilis, Anastasios I., Karachaliou, Chrysoula-Evangelia, Samara, Pinelopi, Ioannou, Kyriaki, Selemenakis, Platon, Kostopoulos, Ioannis V., Kavrochorianou, Nadia, Kalbacher, Hubert, Livaniou, Evangelia, Haralambous, Sylva, Kotsinas, Athanasios, Farzaneh, Farzin, Trougakos, Ioannis P., Voelter, Wolfgang, Dimopoulos, Meletios-Athanasios, Bamias, Aristotelis, Tsitsilonis, Ourania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896021/
https://www.ncbi.nlm.nih.gov/pubmed/31717548
http://dx.doi.org/10.3390/cancers11111764