Oxygen Tension Regulates Lysosomal Activation and Receptor Tyrosine Kinase Degradation

Oxygen sensing is crucial for adaptation to variable habitats and physiological conditions. Low oxygen tension, or hypoxia, is a common feature of solid tumors, and hypoxic tumors are often more aggressive and resistant to therapy. Here we show that, in cultured mammalian cells, hypoxia suppressed l...

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Detalles Bibliográficos
Autores principales: Hong, Jaewoo, Wuest, Todd R., Min, Yongfen, Lin, P. Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896048/
https://www.ncbi.nlm.nih.gov/pubmed/31717697
http://dx.doi.org/10.3390/cancers11111653

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896048/
https://www.ncbi.nlm.nih.gov/pubmed/31717697
http://dx.doi.org/10.3390/cancers11111653

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